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Against the Grain Brewery and Smokehouse is a unique blend of craft brewery and smokehouse located in Louisville, KY. The brainchild of Adam Watson and Travis Kondrat, the brewery focuses on producing creative, handcrafted beers that often feature non-traditional ingredients.

The menu features an array of delicious meats smoked on-site, including pulled pork, brisket, and ribs. Their menu also includes a variety of specialty sandwiches, such as the "Skeptic" – featuring burnt ends and served with barbecue sauce made in-house.